(-)-Epigallocatechin-3-gallate inhibition of ultraviolet B-induced AP-1 activity
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Protective effect of (-)-epigallocatechin gallate on ultraviolet b-induced skin damage in hairless mice
Purpose: To investigate the protective effect of green tea (-)-epigallocatechin gallate (EGCg) on ultraviolet B (UV-B)-induced skin damages in hairless mice in order to develop a natural sunscreen compound for use in skin care products and cosmetics. Methods: EGCg was dissolved in acetone at concentrations of 1.0, 10.0 and 50.0 mg/mL, and topically applied to the skin of hairless mice at doses ...
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Purpose: To investigate the anti-melanogenesis effect of green tea compound, (-)-epigallocatechin-3gallate (EGCG), on B16 murine melanoma cell irradiated by ultraviolet A (UVA) in the search for natural skin-lightening alternative agents. Methods: B16 murine melanoma cells by UVA (9.0 J/cm) for 0 to 32 min and then incubated in Dulbecco's Modified Eagle's Medium (DMEM) with EGCG (0-200 μg/mL) f...
متن کاملEpigallocatechin gallate eye drops protect against ultraviolet B–induced corneal oxidative damage in mice
PURPOSE Ultraviolet B (UVB) radiation from sunlight is a known risk factor for human corneal injury. The aim of the present study was to investigate the protective effects of green tea polyphenol epigallocatechin gallate (EGCG) on UVB radiation-induced corneal oxidative damage in male imprinting control region (ICR) mice. METHODS Corneal oxidative damage was induced by exposure to UVB radiati...
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Background and Objective: The rate of survival in acute promyelocytic leukemia (APL) can dramatically improve, if the patients receive all-trans-retinoic acid (ATRA) treatment. However, this drugchr('39')s toxicity is a major problem in APL treatment. Previous researches have demonstrated that phyto-polyphenols such as epigallocatechin gallate (EGCG) and kaempferol cause apoptosis in hematopoie...
متن کاملEpigallocatechin-3-Gallate Ameliorates Alcohol-Induced Liver Injury in Rats
Endotoxemia is a common event in alcoholic liver disease. Elevated intestinal permeability is the major factor involved in the mechanism of alcoholic endotoxemia and the pathogenesis of alcoholic liver disease. This study examined the effect of epigallocatechin-3-gallate (EGCG) on alcohol-induced gut leakiness, and explored the related mechanisms involved in its protection against alcohol-induc...
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ژورنال
عنوان ژورنال: Carcinogenesis
سال: 1998
ISSN: 1460-2180
DOI: 10.1093/carcin/19.12.2201